I know this will be very exciting for many of you. For work, I was asked to read an article and give a summary of it. This is a review article on acute pulmonary embolisms and how they are treated and dealt with, mainly in the hospital setting.
For your pleasure, if you want to go and find the article:
Agnelli, Giancarlo and Cecilia Becattini. (2010). Acute Pulmonary Embolism. The New England Journal of Medicine, 363(3), 266-74.
A pulmonary embolism is a serious problem that should be considered in several classes of patients. Those with new or worsening difficulty breathing, chest pain or sustained hypotension without an obvious alternative cause should be assumed until proven otherwise.
Each patient should undergo a clinical probability assessment to determine the likelihood of the patient experiencing a PE through either clinical judgment or clinical decision rules (Wells and revised Geneva scores). During the assessment, the patient is determined to be hemodynamically stable or unstable. The stable category is split into two further categories: low/intermediate clinical probability and high clinical probability. Those with the high clinical probability will proceed to the CT scan to confirm or rule out the presence of a pulmonary embolism. The low/intermediate clinical probability group will receive D-dimer testing. The results of that test will determine the next step for the patient. Caution should be used for elderly patients, pregnant women and patients with cancer as the specificity of an increased D-dimer level is reduced in these populations. A normal D-dimer result rules out a pulmonary embolism. If it is elevated, the patient is sent to the CT scanner to determine the presence or absence of a PE.